For active immunization against measles, mumps and rubella in children from 12 months to 10 years of age. Second dose of MMR is usually advocated any time before the age of 6 years (elementary school entry 4-6 years).In children above 10 years, adolescents and adults, Measles and Rubella (MR) vaccine is recommended. Revaccination may seroconvert primary failures or boost antibody titres of previously vaccinated individuals whose titers have declined. The Advisory Committee on Immunization Practices (ACIP) recommends administration of the first dose of MMR at 12-15 months of age and administration of the second dose of MMR at 4-6 years of age. The vaccine can be safely and effectively given simultaneously with DTP, DT, TT, Td, BCG, Polio vaccine (OPV and IPV), Haemophilus influenzae type b, Hepatitis B, or Yellow fever vaccine or vitamin A supplementation.